| 发明名称 |
ARYLINDENOPYRIDINES AND ARYLINDENOPYRIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONIST |
| 摘要 |
<p>This invention provides novel arylindenopyridines and arylindenopyrimidines of formula (I), (II) wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.</p> |
| 申请公布号 |
WO2005042500(A1) |
申请公布日期 |
2005.05.12 |
| 申请号 |
WO2003US31471 |
申请日期 |
2003.10.03 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
HEINTZELMAN, GEOFFREY, R.;BULLINGTON, JAMES, L.;RUPERT, KENNETH, C. |
| 分类号 |
C07D221/16;C07D239/70;C07D401/04;C07D401/06;C07D401/12;C07D405/04;C07D405/14;C07D409/04;C07D417/04;(IPC1-7):C07D239/70;A61K31/535;A61K31/505;C07D405/12 |
主分类号 |
C07D221/16 |
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