发明名称 |
ПРОИЗВОДНЫЕ 4-(ИМИДАЗОЛ-5-ИЛ)-2-(4-СУЛЬФОАНИЛИНО)ПИРИМИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩИМ ДЕЙСТВИЕМ ПО ОТНОШЕНИЮ К CDK |
摘要 |
Compounds of the formula (I): wherein R1, R2, R3, R4, R5 and p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man. |
申请公布号 |
RU2004130440(A) |
申请公布日期 |
2005.05.10 |
申请号 |
RU20040130440 |
申请日期 |
2003.03.06 |
申请人 |
АСТРАЗЕНЕКА АБ (SE) |
发明人 |
НЬЮКОМБ Николас Джон (GB);ТОМАС Эндрью Питер (GB) |
分类号 |
A61K31/506;A61K31/5377;A61K31/63;A61P1/00;A61P1/16;A61P1/18;A61P9/00;A61P9/10;A61P11/00;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P17/12;A61P17/14;A61P19/00;A61P19/02;A61P19/08;A61P21/00;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D413/04;C07D413/14;C07D417/14 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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