发明名称 |
DEOXYNOJIRIMYCIN ANALOGUES AND THEIR USES AS GLUCOSYLCERAMIDASE INHIBITORS |
摘要 |
<p>The invention provides a new class of deoxynojirimycin analogues, or pharmaceutically acceptable salts thereof which can suitably be used for the treatment of a disease selected from the group consisting of insulin resistance, Gauger disease, inflammatory diseases, hyperpigmentation and/or inflammatory skin conditions, overweight and obesity, lysosomal storage disorders, fungal diseases, melanoma and other tumors, and microbacterial infections. The invention further provides a pharmaceutical composition comprising said deoxynojirimycon analogue, or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.</p> |
申请公布号 |
WO2005040118(A1) |
申请公布日期 |
2005.05.06 |
申请号 |
WO2004NL00761 |
申请日期 |
2004.10.29 |
申请人 |
ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM;AERTS, JOHANNES, MARIA, FRANCISCUS, GERARDUS |
发明人 |
AERTS, JOHANNES, MARIA, FRANCISCUS, GERARDUS |
分类号 |
C07D211/46;(IPC1-7):C07D211/46;A61K31/445 |
主分类号 |
C07D211/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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