| 发明名称 |
INDUCING CELLULAR IMMUNE RESPONSES TO P53 USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS |
| 摘要 |
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmnaceutical compositions and methods of use in the prevention and treatment of cancer. |
| 申请公布号 |
EP1237564(A4) |
申请公布日期 |
2005.05.04 |
| 申请号 |
EP20000984231 |
申请日期 |
2000.12.11 |
| 申请人 |
EPIMMUNE, INC. |
发明人 |
FIKES, JOHN;SETTE, ALESSANDRO;SIDNEY, JOHN;SOUTHWOOD, SCOTT;CHESNUT, ROBERT;CELIS, ESTEBAN;KEOGH, ELISSA |
| 分类号 |
C12N15/09;A61K9/127;A61K35/12;A61K35/14;A61K39/00;A61K39/385;A61K39/39;A61P35/00;C07K7/06;C07K7/08;C07K14/47;C07K14/82 |
主分类号 |
C12N15/09 |
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