发明名称 |
GLYCONJUGATES COMPRISING CARBOHYDRATE EPITOPES, METHODS FOR THEIRSYNTHESIS, AND THEIR USE FOR THE TREATMENT OR PROPHYLAXIS OF CANCER |
摘要 |
The present invention provides novel glycosides and glycoconjugates, glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycopeptides as disclosed herein, either in conjugated form or unconjugated and in combination with a suitable immunogenic carrier. |
申请公布号 |
EP1527081(A1) |
申请公布日期 |
2005.05.04 |
申请号 |
EP20030771674 |
申请日期 |
2003.07.18 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
DANISHEFSKY, SAMUEL J.;COLTART, DON M.;KEDING, STACY J.;BISWAS, KAUSTAV;LIVINGSTON, PHILIP O.;RAGUPATHI, GOVINDASWAMI;ALLEN, JENNIFER R.;WILLIAMS, LAWRENCE |
分类号 |
A61K31/715;A61K38/00;A61K39/00;A61P35/00;A61P43/00;C07H15/04;C07H15/10;C07H15/18;C07K1/107;C07K5/078;C07K9/00;C07K14/435;(IPC1-7):C07H15/10;C07K4/00;C08B37/00;A61K38/14 |
主分类号 |
A61K31/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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