发明名称 |
CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN |
摘要 |
This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: Formula (I) wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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申请公布号 |
EA005648(B1) |
申请公布日期 |
2005.04.28 |
申请号 |
EA20030000042 |
申请日期 |
2001.07.16 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
CODD, ELLEN, E.;SHANK, RICHARD, P.;ROGERS, KATHERINE, E.;PLATA-SALAMAN, CARLOS, R.;ZHAO, BOYU |
分类号 |
A61P25/04;A61K31/27;A61P25/06;(IPC1-7):A61P25/06 |
主分类号 |
A61P25/04 |
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地址 |
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