发明名称 CYCLOPROPYL METHANONE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF
摘要 The invention relates to a compound of formula (I), wherein n ranges from 1 to 6, A is aryl such as phenyl or naphtyle, or monocyclic heteroaryl such as thienyl, furyl or pyrrolyl; aryl or heteroaryl being substituted, if necessary; B is *NR1R2, wherein R1 and R2 represent independently from each other a C1-6 alkyl group, or R1 and R2 represent together a C2-6 alkyliden group, C1-3 alkyliden-O-C1-3 alkyliden group, or C1-3 alkyliden-N(R3)- C1-3 alkyliden group wherein R3 is a hydrogen atom, a C1-3 alkyl or C1-6 alkylcarbonyl group, or * an aminocycle such as aziridine, azetidine, pyrrolidine, piperidine bound to a O-(C)n group by aminocycle carbon; the groups R1, R2 and aminocycle being, if necessary and the O-(C)n group represents a O-C1-6 alkyliden if necessary substituted group. Said invention can be used for therapy.
申请公布号 WO2005037810(A2) 申请公布日期 2005.04.28
申请号 WO2004FR02637 申请日期 2004.10.15
申请人 SANOFI-AVENTIS;DIAZ MARTIN, JUAN ANTONIO;ESCRIBANO ARENALES, BEATRIZ;MARTIN ESCUDERO PEREZ, ULPIANO 发明人 DIAZ MARTIN, JUAN ANTONIO;ESCRIBANO ARENALES, BEATRIZ;MARTIN ESCUDERO PEREZ, ULPIANO
分类号 C07C217/22;C07C225/18;C07D207/08;C07D243/08;C07D295/092;C07D295/185;C07D295/205;C07D307/12;C07D307/46;C07D333/10;C07D333/22 主分类号 C07C217/22
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