发明名称 Therapeutic quinoline compounds with 5-HT-antagonistic properties.
摘要 Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT<SUB>1B </SUB>and 5HT<SUB>1D </SUB>antagonists.
申请公布号 ZA200403202(B) 申请公布日期 2005.04.26
申请号 ZA20040003202 申请日期 2004.04.28
申请人 ASTRAZENECA AB. 发明人 MARC CHAPDELAINE;MARKUS HAEBERLEIN;JOHN MCCAULEY;DANIEL SOHN;TIMOTHY DAVENPORT;CAREY HORCHLER;EDWARD PIERSON
分类号 C07D215/48;A61K31/496;A61K31/5377;A61K31/551;A61P1/00;A61P3/04;A61P5/00;A61P9/00;A61P15/00;A61P15/10;A61P21/02;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D207/14;C07D215/22;C07D215/233;C07D215/42;C07D241/04;C07D243/08;C07D265/30;C07D311/24;C07D401/04;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D413/06;C07D413/14;C07D417/12 主分类号 C07D215/48
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