发明名称 Thiol-based NAALADase inhibitors
摘要 This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-beta activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
申请公布号 US2005085503(A1) 申请公布日期 2005.04.21
申请号 US20040959199 申请日期 2004.10.07
申请人 发明人 TSUKAMOTO TAKASHI;MAJER PAVEL;STOERMER DORIS;SLUSHER BARBARA S.
分类号 A61P9/00;A61K31/192;A61K31/194;A61K31/277;A61P13/08;A61P25/00;A61P25/02;A61P25/04;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P27/06;A61P35/00;A61P43/00;C07C323/52;C07C323/56;C07C323/58;C07C323/59;C07C323/60;C07C323/62;C07C323/65;(IPC1-7):C07D217/12;C07D277/80;C07D263/60;A61K31/47;A61K31/428;A61K31/423;A61K31/418 主分类号 A61P9/00
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