PARTICULATE MATERIALS

摘要

A particulate coformulation, each particle comprising a core of an active substance surrounded by an excipient coating, the particles having a volume mean diameter of 10 mum or less, which on oral administration releases the active substance at a rate such that the time (T_max) taken to attain the maximum active concentration in the bloodstream is one hour or less. The coformulation may be made using a Nektar(TM) SCF particle formation process.