NOVEL DNA SEQUENCES OF THE BOTULINUM NEUROTOXIN COMPLEX OF CLOSTRIDIUM BOTULINUM TYPE A-HALL (ALLERGAN) STRAIN FOR PRODUCTION OF THERAPEUTICS

摘要

This invention broadly relates to recombinant DNA technology, molecular biology, neuroscience, and medicine.. Particularly, the present invention features novel sequences of the toxin and non-toxin components of the Clostridium botulinum toxin type A-Hall (Allergan) strain complex as well as the expression vector system in a heterologous organism and methods to express such nucleic acid sequences.