Method for measuring FceRII/CD23 IgE receptor in human feces as an indicator of a TH2 predominant immune response involved in gastrointestinal illnesses

摘要

A method and apparatus for measuring FcepsilonRII/CD23 IgE receptor in human feces or other biological specimens as an indicator of a TH2 immune response indicative of gastrointestinal illnesses such as ulcerative colitis and food allergy is described. The apparatus consists of either a qualitative or quantitative enzyme-linked immunoassay or other immunoassay that utilizes antibodies specific to human FcepsilonRII/CD23 IgE receptor for the measurement of endogenous FcepsilonRII/CD23 IgE receptor in human feces. The method and apparatus can be used by healthcare providers as an aid for determining gastrointestinal illnesses that are predominantly a TH2 predominant immune response such as ulcerative colitis, large bowel Crohn's disease (IC-like Crohn's disease), allergic colitis (food allergy) and parasitic infections.