发明名称 |
Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium |
摘要 |
A glutamine-auxotrophic human cell transfected with an exogenous DNA sequence encoding a protein or an exogenous DNA sequence capable of altering the expression of an endogenous gene encoding a protein and an exogenous DNA sequence encoding a glutamine synthetase, wherein these exogenous DNA sequences are located on one or more than one DNA construct, said transfected cell capable of producing said protein and capable of growing in a glutamine-free medium.
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申请公布号 |
US2005084928(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
US20040501777 |
申请日期 |
2004.07.19 |
申请人 |
BIRCH JOHN R.;BORASTON ROBERT C.;SHAW MARTYN |
发明人 |
BIRCH JOHN R.;BORASTON ROBERT C.;SHAW MARTYN |
分类号 |
C07K14/505;C12N5/09;C12N15/85;(IPC1-7):C07H21/04;C12N5/08 |
主分类号 |
C07K14/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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