The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozym e. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
申请公布号
CA2535930(A1)
申请公布日期
2005.04.21
申请号
CA20042535930
申请日期
2004.08.19
申请人
IRM LLC
发明人
LIU, HONG;HE, YUN;CHATTERJEE, ARNAB;TULLY, DAVID C.;KARANEWSKY, DONALD S.;WOODMANSEE, DAVID;MUTNICK, DANIEL;GUO, JIANHUA;BURSULAYA, BADRY;ALPER, PHILLIP B.