发明名称 |
Antibody composition specifically binding to ganglioside GM2 |
摘要 |
An anti-ganglioside GM2 antibody composition having enhanced effector function which is useful as a medicament has been desired. The present invention provides an antibody composition comprising an antibody molecule which specifically binds to ganglioside GM2 and has complex type N-glycoside-linked sugar chains in the Fc region, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains; a transformant which produces the antibody composition; a process for producing the antibody composition; and a pharmaceutical composition comprising the antibody composition. |
申请公布号 |
AU2004279736(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
AU20040279736 |
申请日期 |
2004.10.08 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
MASAKO WAKITANI;SHIGERU IIDA;KENYA SHITARA;MITSUO SATOH;RINPEI NIWA;KAZUHISA UCHIDA;MIHO INOUE |
分类号 |
C07K16/30;A61P35/00;C12N15/13;C12P21/08 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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