| 发明名称 |
МОЛЕКУЛЯРНЫЕ МИМЕТИКИ ЭПИТОПОВ МЕНИНГОКОККА В, КОТОРЫЕ ВЫЗЫВАЮТ ВЫРАБОТКУ ФУНКЦИОНАЛЬНО АКТИВНЫХ АНТИТЕЛ |
| 摘要 |
Molecular mimetics of a surface-exposed epitope on loop 4 of PorA of Neisseria meningitidis serogroup B (MenB) P1.2 serosubtype and antibodies produced against the same are disclosed. Compositions containing such molecular mimetics or the antibodies thereto can be used to prevent MenB disease, as well as for diagnosis of MenB infection. |
| 申请公布号 |
RU2003133300(A) |
申请公布日期 |
2005.04.20 |
| 申请号 |
RU20030133300 |
申请日期 |
2002.04.11 |
| 申请人 |
ЧИРОН КОРПОРЕЙШН (US);ЧИЛДРЕН`З ХОСПИТАЛ ОКЛЕНД РИСЕРЧ ИНСТИТЬЮТ (US) |
发明人 |
ГРАНОФФ Дэн (US);МОЭ Грегори (US);РАППУОЛИ Рино (IT) |
| 分类号 |
G01N33/53;A61K39/00;A61K39/095;A61K39/395;A61K39/40;A61P31/04;A61P43/00;C07K1/22;C07K2/00;C07K14/22;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12N15/63;C12P21/00;C12P21/02;C12P21/08;C12R1/36;G01N33/569 |
主分类号 |
G01N33/53 |
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