发明名称 ОЛИГОПЕПТИДЫ ОСТЕОГЕННОГО РОСТА В КАЧЕСТВЕ СТИМУЛЯТОРОВ ГЕМАТОПОЭЗА
摘要 FIELD: medicine, peptides. ^ SUBSTANCE: invention relates to osteogenic growth oligopeptides used as stimulators of hemopoiesis. Invention proposes using an oligopeptide of molecular mass in the range from 200 to 1000 Da, comprising one of the following sequence: Tyr-Gly-Phe-Gly-Gly, Met-Tyr-Gly-Phe-Gly-Gly used in preparing a pharmaceutical composition and enhancing mobilization of hemopoietic stem cells from many differentiation line into peripheral blood, in particular, CD34-positive hemopoietic stem cells. Advantage of the invention involves expanding field in using oligopeptides used in stimulation of hemopoiesis. ^ EFFECT: enhanced and valuable properties of oligopeptides. ^ 34 cl, 2 tbl, 7 dwg, 4 ex
申请公布号 RU2004105258(A) 申请公布日期 2005.04.20
申请号 RU20040105258 申请日期 2001.07.29
申请人 Йисум Ресеч Девелопмент Компании оф дзе Хиброу Юнивесити оф Иерусалим (IL) 发明人 БАБ Итай (IL);ХОРЕВ Михаил (IL);ШТЕИР Арье (IL);МУХЛРАД Андраш (IL);МАНСУР Нура (IL);ГУРЕВИЧ Ольга (IL);ГРИНБЕРГ Цви (IL);РОСИНИ Серджио (IT);ТРАСЦИАТИ Сильвиа (IT);ПЕТРИНИ Марио (IT)
分类号 A61K38/07;A61K38/08;A61P7/00;A61P35/02;C07K7/00;C12N5/00;C12N5/071;C12N5/0789 主分类号 A61K38/07
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