COMPUESTOS DERIVADOS 3-(PIRIDIN-2-IL)-4-HETEROARIL-PIRAZOL SUSTITUIDOS, ANTAGONISTAS DE AIK5 Y/O AIK4; COMPOSICION FARMACEUTICA Y USO DEL COMPUESTO EN EL TRATAMIENTO DE DESORDENES FIBROTICOS COMO ESCLERODERMIA, LUPUS NEFRITICO, CICATRIZACION DE HERID

摘要

The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I).