发明名称 |
Inhibitors of serine proteases, particularly HVC NS3-NS4A protease |
摘要 |
The present invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are useful as antiviral agents. The invention further relates to pharmaceutically acceptable compositions comprising said compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a pharmaceutical composition comprising a compound of this invention.
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申请公布号 |
US2005080017(A1) |
申请公布日期 |
2005.04.14 |
申请号 |
US20040821663 |
申请日期 |
2004.04.09 |
申请人 |
COTTRELL KEVIN M.;MAXWELL JOHN;PERNI ROBERT B.;PITLIK JANOS |
发明人 |
COTTRELL KEVIN M.;MAXWELL JOHN;PERNI ROBERT B.;PITLIK JANOS |
分类号 |
A61K31/40;A61K38/04;C07D403/12;C07K5/04;C07K5/10;(IPC1-7):A61K38/04;C07D43/14 |
主分类号 |
A61K31/40 |
代理机构 |
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主权项 |
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地址 |
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