| 发明名称 |
High affinity fusion proteins and therapeutic and diagnostic methods for use |
| 摘要 |
High affinity fusion proteins ("trapbodies"), capable of binding and inhibiting the activity of soluble, interacting proteins ("SIPs") are described. The trapbodies are multimers, preferably dimers, of SIP-specific fusion polypeptides which comprise SIP binding domains derived from SIP targets and/or anti-SIP immunoglobulins, as well as multimerizing components.
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| 申请公布号 |
US2005074855(A1) |
申请公布日期 |
2005.04.07 |
| 申请号 |
US20030610452 |
申请日期 |
2003.06.30 |
| 申请人 |
STAHL NEIL;YANCOPOULOS GEORGE D, |
发明人 |
STAHL NEIL;YANCOPOULOS GEORGE D, |
| 分类号 |
C07K14/715;C07K16/24;C07K16/46;C12N15/62;C12P21/04;(IPC1-7):C07H21/04;C12P21/02;C12N5/06;C07K14/52 |
主分类号 |
C07K14/715 |
| 代理机构 |
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