发明名称 Targeted release of nitric oxide in the CNS circulation for modulating the BBB and treating disorders
摘要 A method for delivering molecules to a central nervous system (CNS) of a subject includes supplying the molecules to a blood circulation of the CNS; supplying, to a body of the subject, a carrier system that encapsulates a nitric oxide (NO) facilitator; and applying energy to the carrier system at an energy level sufficient to cause the carrier system to release the NO facilitator in a blood circulation of the subject in a vicinity of a blood-brain barrier (BBB) of the subject and thereby increase passage of the molecules from the blood circulation of the CNS, through the BBB, and into the CNS of the subject.
申请公布号 US2005074506(A1) 申请公布日期 2005.04.07
申请号 US20030678730 申请日期 2003.10.02
申请人 BRAINSGATE LTD. 发明人 NATAN AMIR;SHALEV ALON
分类号 A61K31/21;A61K33/00;A61K41/00;A61K45/06;A61N1/30;A61N1/40;A61N2/02;(IPC1-7):A61K33/00 主分类号 A61K31/21
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