The invention relates to codrugs having improved properties, methods for preparing and administering them, and methods of formulating and administering the codrugs as pharmaceutical preparations. In certain embodiments, the codrugs can be locally administered to deliver the constituent biologically active compound in a sustained-release fashion, reducing systemic concentrations of the biologically active compound.
申请公布号
WO2004112838(A3)
申请公布日期
2005.04.07
申请号
WO2004US16002
申请日期
2004.05.21
申请人
CONTROL DELIVERY SYSTEMS, INC.;ASHTON, PAUL;CHEN, JIANBING;GUO, HONG;CYNKOWSKI, TADEUSZ;CYNKOWSKA, GRAZYNA