| 发明名称 |
LPA receptor agonists and antagonists and methods of use |
| 摘要 |
The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.
|
| 申请公布号 |
US6875757(B2) |
申请公布日期 |
2005.04.05 |
| 申请号 |
US20010811838 |
申请日期 |
2001.03.19 |
| 申请人 |
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
MILLER DUANE D.;TIGYI GABOR;DALTON JAMES T.;SARDAR VINEET M.;ELROD DON B.;XU HUIPING;BAKER DANIEL L.;WANG DEAN;LILIOM KAROLY;FISCHER DAVID J.;VIRAG TAMAS;NUSSER NORA |
| 分类号 |
C12N15/09;A61K31/27;A61K31/66;A61K31/685;A61P17/02;A61P35/00;A61P43/00;C07F9/09;C07F9/10;C07F9/11;C07F9/17;C07F9/22;C07F9/38;C07F9/40;(IPC1-7):A61K31/661;C07F9/06 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
