METHOD OF PREPARING SOLUTION HAVING COMPOSITION OF BIOLOGICAL COMPONENTS

摘要

A method of preparing a solution comprising combining two steps of (1) a ste p of adsorbing a protein having a molecular weight higher than that of albumin , (2) a step of fractionating a protein having a molecular weight higher than that of albumin, and (3) a step of concentrating a protein; a method of preparing a solution comprising separating by the use of a membrane separati on unit exhibiting a permeation ratio of a protein having a molecular weight le ss than 15 thousands to a protein having a molecular weight of 60 thousands or more of 50 or more; and a method of preparing a solution which comprises feeding a raw biological component solution and then a liquid for dilution t o a separating membrane module, and allowing a part of the resultant solution to permeate through a separation membrane while circulating the solution. The method can be advantageously employed for preparing a biological component- containing solution which is suitable for the clinical proteomics using mass analysis, electrophoresis, liquid chromatography, and the like.