SENSITIVE AND RAPID BIODETECTION

摘要

The present invention relates to detecting a target by moving it into proximity to a surface which has affinity for the target. The movement can involve the use of electrophoresis, which can be enhanced by the presence of oxidizing and reducing reagents, which lowers the voltage at which electrophoretic force can be generated. This lower potential allows a broader range of means by which the target can be detected,including detection during concentration, and the ability to detect multiple times without fixation of the target. A tag can be bound to the target so as to confer movement and/or detectability. The target can be molecules, such as nucleic acid or proteins, and is conveniently microorganisms. When immobilized on the surface, the microorganisms can be identified and grown, allowing the determination of the susceptibility of the microorganisms to various antimicrobial drugs.