发明名称 |
Specificity in the detection of anti-rubella IGM antibodies |
摘要 |
This invention particularly discloses an improved immunoassay method for the specific detection of anti-rubella IgM antibodies. This method employs rubella antigens comprising rubella E1 and E2 envelope glycoproteins substantially free of capsid protein. Use of this antigen composition reduces or eliminates nonspecific protein-protein interactions leading to false positive results. A sample diluent comprising urea can also be used in the process to further reduce the occurrence of nonspecific protein-protein interactions. A diagnostic kit to aid in the detection of anti-rubella IgM antibodies is also disclosed.
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申请公布号 |
US6872396(B2) |
申请公布日期 |
2005.03.29 |
申请号 |
US20030696635 |
申请日期 |
2003.10.29 |
申请人 |
VIRAL ANTIGENS, INC. |
发明人 |
DORSETT PRESTON H.;BYRD FRANCES I.;DEVLIN ROBERT F. |
分类号 |
G01N33/569;(IPC1-7):A61K39/20;A61K39/12;C07K14/19;G01N33/53 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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