KALLIKREIN-INHIBITING KUNITZ DOMAIN PROTEINS AND ANALOGUESTHEREOF

摘要

This invention relates to novel BPTI-homologous Kunitz domains, especially L ACI homologues, which inhibit one or more plasma (and/or tissue) kallikreins, and to the therapeutic and diagnostic use of th ese novel proteins. In particular, this invention relate s to Kunitz domains derived from Kunitz domains of human origin and especially to the fi rst Kunitz domain of LACI.