INTERNALISING HUMAN BINDING MOLECULES AGAINST CD72

摘要

The present invention provides internalising human binding molecules that specifically bind to CD72, nucleic acid molecules encoding the internalising human binding molecules, compositions comprising the internalising human binding molecules and methods of identifying or producing the internalising human binding molecules. In a preferred aspect, the invention provides immunoconjugates comprising an internalising human binding molecules that specifically binds to CD72. The internalising human binding molecules and immunoconjugates comprising an internalising human binding molecule can be used in the diagnosis and treatment of B cell associated disorders.