| 发明名称 |
PYRROLIDINE-2-CARBONITRILE DERIVATIVES AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) |
| 摘要 |
<p>The present invention relates to compounds of formula (I), (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, b-cell failure, obesity, satiety disorders, atherosclerosis, and various immunomodulatory diseases.</p> |
| 申请公布号 |
WO2005023762(A1) |
申请公布日期 |
2005.03.17 |
| 申请号 |
WO2004US28886 |
申请日期 |
2004.09.07 |
| 申请人 |
ABBOTT LABORATORIES;PEI, ZHONGHUA;LI, XIAOFENG;LONGENECKER, KENTON, L.;SHAM, HING, L.;WIEDEMAN, PAUL, E. |
发明人 |
PEI, ZHONGHUA;LI, XIAOFENG;LONGENECKER, KENTON, L.;SHAM, HING, L.;WIEDEMAN, PAUL, E. |
| 分类号 |
A61P3/04;A61P3/10;C07D207/16;C07D401/14;(IPC1-7):C07D207/16;A61K31/401;A61K31/470;A61K31/443;C07D409/14;C07D405/14;C07D403/14 |
主分类号 |
A61P3/04 |
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