| 发明名称 |
CYCLOHEXYL PROSTAGLANDIN ANALOGS AS EP4-RECEPTOR AGONISTS |
| 摘要 |
<p>The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EP4 agonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following formula I wherein the wavy segments represent alpha or beta bond, dashed line represents the presence or absence of a bond W, Y, Z, R, R<1> , R<2> and R<3> are as defined in the specification.</p> |
| 申请公布号 |
WO2005023267(A1) |
申请公布日期 |
2005.03.17 |
| 申请号 |
WO2004US26607 |
申请日期 |
2004.08.16 |
| 申请人 |
ALLERGAN, INC.;OLD, DAVID, W.;BURK, ROBERT, M.;DINH, THANG, D. |
发明人 |
OLD, DAVID, W.;BURK, ROBERT, M.;DINH, THANG, D. |
| 分类号 |
A61K31/557;A61K31/662;A61P27/06;C07C59/90;C07C69/738;C07D333/56;C07D333/62;C07F9/38;C07F9/40;C07F9/6553;(IPC1-7):A61K31/557;C07C69/743;C07C235/30;C07C49/753;C07D257/04;C07F9/08 |
主分类号 |
A61K31/557 |
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