发明名称 |
Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini |
摘要 |
The present invention relates to bicyclic nucleosides and oligomeric compounds comprising at least one such nucleoside. These oligomeric compounds typically have enhanced binding affinity and nuclease resistance properties compared to unmodified oligomeric compounds. The oligomeric compounds are useful, for example, for investigative and therapeutic purposes.
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申请公布号 |
US2005059066(A1) |
申请公布日期 |
2005.03.17 |
申请号 |
US20040935958 |
申请日期 |
2004.09.08 |
申请人 |
SWAYZE ERIC E.;MIGAWA MICHAEL T.;WYRZYKIEWICZ TADEUSZ KRZYSZTOF |
发明人 |
SWAYZE ERIC E.;MIGAWA MICHAEL T.;WYRZYKIEWICZ TADEUSZ KRZYSZTOF |
分类号 |
C07H21/04;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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