发明名称 Method of preventing of delaying the onset and progression of Alzheimer's disease and related disorders
摘要 The present invention relates, in general, to a method of preventing or delaying the onset of Alzheimer's disease and related neurodegenerative disorders. The invention also relates to a method of treating Alzheimer's disease and related neurodegenerative disorders so as to ameliorate the further progress of symptoms. The methods involve the administration of a non-steroidal anti-inflammatory agent and/or a histamine H2 receptor blocking agent. According to indication, the present method can be applied to individuals who are currently asymptomatic but at risk of developing Alzheimer's disease, to individuals who have mild cognitive symptoms that may either denote an incipient prodrome of Alzheimer's disease or represent early symptoms (prodromal stage), or to individuals who have a clinical diagnosis of Alzheimer's disease.
申请公布号 US6867236(B1) 申请公布日期 2005.03.15
申请号 US19990300789 申请日期 1999.04.28
申请人 DUKE UNIVERSITY 发明人 BREITNER JOHN C. S.;WELSH-BOHMER KATHLEEN A.
分类号 A61K31/00;A61K31/167;A61K31/192;A61K31/65;A61P25/14;A61P25/16;A61P25/28;(IPC1-7):A61K31/60;A61K31/615;A61K31/54;A61K31/44 主分类号 A61K31/00
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