发明名称 (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor.
摘要 The present invention relates to (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and pharmaceutically acceptable salts thereof, compositions comprising (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and methods for treating or preventing a disorder alleviated by inhibiting dopamine reuptake. In one embodiment, the disorder is attention-deficit disorder, depression, obesity, Parkinson's disease, a tic disorder, or an addictive disorder. The (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or pharmaceutically acceptable salt thereof is preferably substantially free of its corresponding (+)-enantiomer.
申请公布号 ZA200401545(B) 申请公布日期 2005.03.10
申请号 ZA20040001545 申请日期 2004.02.25
申请人 DOV PHARMACEUTICAL, INC. 发明人 ARNOLD STAN LIPPA;JOSEPH WILLIAM EPSTEIN
分类号 C07D471/08;A61K9/14;A61K31/439;A61K45/00;A61P3/04;A61P25/00;A61P25/16;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P43/00;C07D209/52 主分类号 C07D471/08
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