ESTIMATION OF ACTIVITY OR INHIBITION OF PROCESSES INVOLVED IN NUCLEIC ACID MODIFICATION USING CHEMILUMINESCENCE QUENCHING
摘要
A method for determining the activity of a substance capable of altering the structure of a nucleic acid molecule from a first to a second state which is based upon the use of labelled nucleic acid molecules and/or complementary oligonucleotides. The label is a chemiluminescent molecule and a corresponding quencher molecule whose optical properties are different depending upon whether the nucleic acid molecule exist in said first or second state.
申请公布号
WO2005021784(A2)
申请公布日期
2005.03.10
申请号
WO2004GB03633
申请日期
2004.08.26
申请人
MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED;WEEKS, IAN;BROWN, RICHARD, CHARLES;MORBY, ANDREW;BERRY, COLIN
发明人
WEEKS, IAN;BROWN, RICHARD, CHARLES;MORBY, ANDREW;BERRY, COLIN