| 发明名称 |
BLOCKADE OF MTOR TO PREVENT A HORMONAL ADAPTIVE RESPONSE |
| 摘要 |
One embodiment of the present invention is directed to the use of an mTOR inhibitor, such as farnesylthiosalicylic acid (FTS), to prevent a hormonal adaptive response during hormonal deprivation treatment of a hormonal responsive cancer. FIG. 4 represents the effect of FTS on E2 stimulated grow th of MCF-7 and LTED cells.
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| 申请公布号 |
CA2535944(A1) |
申请公布日期 |
2005.03.03 |
| 申请号 |
CA20042535944 |
申请日期 |
2004.08.20 |
| 申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
MCMAHON, LLOYD P.;SANTEN, RICHARD J.;YUE, WEI;LAWRENCE, JOHN C., JR. |
| 分类号 |
A61K31/20;A61K;A61K31/135 |
主分类号 |
A61K31/20 |
| 代理机构 |
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