| 发明名称 |
Method for identifying a PDE IV inhibitor |
| 摘要 |
<p>This invention relates to a compound which selectively inhibits PDE IV and wherein the IC50 value for the PDE IV catalytic form which binds rolipram with a high affinity is lower than the IC50 value for the form which binds rolipram with a low affinity and to uses thereof in therapy.</p> |
| 申请公布号 |
SI710109(T1) |
申请公布日期 |
2005.02.28 |
| 申请号 |
SI19940030469T |
申请日期 |
1994.06.17 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
BARNETTE MARY S.;TORPHY THEODORE J.;CHRISTENSEN SIEGFRIED B. IV |
| 分类号 |
C07D487/04;A61K31/00;A61K31/275;A61K31/277;A61K31/40;A61K31/47;A61K31/485;A61K31/505;A61K45/00;A61P29/00;A61P43/00;C07C233/56;C07C255/46;C07D207/12;(IPC1-7):A61K31/275 |
主分类号 |
C07D487/04 |
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