发明名称 КОМБИНАЦИЯ, ВКЛЮЧАЮЩАЯ N-{5-[4-(4-МЕТИЛПИПНРАЗИНОМЕТИЛ)БЕНЗОИЛАМИДО]-2-МЕТИЛФЕНИЛ}-4-(3-ПИРИДИЛ)- 2-ПИРИМИДИНА МИН И ХИМИОТЕРАПЕВТИЧЕСКИЙ АГЕНТ
摘要 A method of treating a warm-blooded animal, especially a human, having a proliferative disease or acute or chronic transplant rejection comprising administering to the animal a combination which comprises (a) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and (b) a chemotherapeutic agent selected from antineoplastic agents, especially as defined herein, and agents effective in treating acute or chronic transplant rejection; a combination comprising (a) and (b) as defined above and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.
申请公布号 RU2003135786(A) 申请公布日期 2005.02.27
申请号 RU20030135786 申请日期 2002.05.15
申请人 НОВАРТИС АГ (CH) 发明人 БРУНС Кристиан (DE);БУХДУНГЕР Элизабет (DE);О`РЕЙЛЛИ Теренс (CH);СИЛБЕРМАН Сандра Лита (US);ВАРТМАНН Маркус (CH);ВЕККБЕККЕР Гизберт (CH)
分类号 A61K45/00;A61K31/506;A61K31/675;A61K45/06;A61P35/00;A61P35/04;A61P37/06;A61P43/00 主分类号 A61K45/00
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