КОМПОЗИЦИЯ ИЗ ПЕПТИДОВ, ОБЛАДАЮЩАЯ ИММУНОРЕГУЛЯТОРНЫМ СВОЙСТВОМ

摘要

FIELD: medicine, immunology, peptides. ^ SUBSTANCE: invention relates to a new composition of biologically active substances. Invention proposes the composition comprising of peptides of the formula: Arg-Gly-Asp and H-Tyr-X-Y-Glu-OH wherein X means Gln and/or Glu; Y means Cys(acm) and/or Cys that elicits ability to inhibit the proliferative response for phytohemagglutinin, to induce the suppressive activity of mononuclear cells and ability of peptides to induce secretion of immunosuppressive cytokines of grouth-transforming factor-beta1 and interleukin-10 (IL-10). The composition can be prepared by a simple procedure. ^ EFFECT: valuable biological properties of composition. ^ 3 cl, 16 tbl, 9 ex