发明名称 |
Core 1 beta3-galactosyltransferase specific molecular chaperones, nucleic acids, and methods of use thereof |
摘要 |
Core 1 beta3-galactosyl transferase specific molecular chaperones (Cosmc-1) and nucleic acids encoding the core 1 beta3-galactosyl transferase specific molecular chaperones or proteins having core 1 beta3-galactosyl transferase specific molecular chaperone activity are described. The polynucleotides encoding Cosmc-1 can be used to transform or transfect host cells for producing substantially pure forms of active forms of core 1 beta3-galactosyl transferase and/or for use in an expression system for post-translational core 1 glycosylation of proteins or peptides produced within the expression system, for example, glycosylation via a beta3-linkage, of an N-acetylgalactosamine linked to a serine, threonine or other linking amino acid on peptides or proteins requiring O-, N-, or S-linked glycosylation.
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申请公布号 |
US2005037477(A1) |
申请公布日期 |
2005.02.17 |
申请号 |
US20030661049 |
申请日期 |
2003.09.12 |
申请人 |
CUMMINGS RICHARD D.;JU TONGZHONG |
发明人 |
CUMMINGS RICHARD D.;JU TONGZHONG |
分类号 |
C07K14/47;(IPC1-7):C12N9/64;C07H21/04 |
主分类号 |
C07K14/47 |
代理机构 |
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地址 |
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