摘要 |
Novel therapeutic targets in the treatment of neuroimmunological and neurodegenerative disorders. Accordingly, methods of treating a neurodegenerative disorder in a patient, as well as inhibiting the release of a proinflammatory cytokine, comprising the step of contacting a target cell with a therapeutically effective amount of a cholinergic agonist, such as those chosen from the group consisting of acetycholine, nicotine, choline, galantamine, cytisine, GTS-21, or derivatives thereof, wherein the target cell is a microglia is provided. |
申请人 |
UNIVERSITY OF SOUTH FLORIDA;SHYTLE, DOUGLAS;TAN, JUN;SANBERG, PAUL, R. |
发明人 |
SHYTLE, DOUGLAS;TAN, JUN;SANBERG, PAUL, R. |