THE ARTIFICIAL CPG SINGLE STRAND DEOXIDATION OLIGONUCLEOTIDE AND ITS ANTIVIRAL USES

摘要

The present invention disclosed a set of artificial ODNs which contain one or more CpG(s), the said ODNs can stimulate human PBMC to produce antiviral substances. These antiviral substances make cell avoid of the attack from virus, the influenza virus and the single strand plus RNA virus are preferred, such as hepatitis C virus, dengue virus and Japanese encephalitis virus. Moreover, the antiviral uses of artificial CpG ODNs and its uses for treating and preventing viral infection are also provided.