发明名称 |
Target-specific activatable polymeric imaging agents |
摘要 |
A target-specific image-enhancing agent for medical imaging comprises an extended poly(amino acid), wherein at least 90 percent of the amino acid residues are conjugated to signal-generating moieties attached to signal-controlling moieties via bonds that are cleavable by a physiological substance produced by the target. The image-enhancing agent becomes activated when the bonds is cleaved by the physiological substance. The image-enhancing agent is used in detecting and/or diagnosing a disease that is characterized by an overproduction of the substance.
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申请公布号 |
US2005036947(A1) |
申请公布日期 |
2005.02.17 |
申请号 |
US20030638888 |
申请日期 |
2003.08.12 |
申请人 |
GENERAL ELECTRIC COMPANY |
发明人 |
UZGIRIS EGIDIJUS EDWARD;AMARATUNGA MOHAN MARK |
分类号 |
A61K49/10;(IPC1-7):A61K49/00 |
主分类号 |
A61K49/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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