METHOD AND KIT FOR ASSESSING THE RISK OF CARDIOVASCULAR PATHOLOGIES WITH THEROMATOUS ETIOLOGY
摘要
The invention relates to a molecolar method for in vitro assessment of the predisposition of a subject to develop cardiovascular pathologies, associated with rupture of an atherosclerotic plaque. The method is caracterized by the identification of a polymorphism in the COX-2 gone promotor, using genomic DNA sample(s) of the subject or a group of subjects. Moreover the invention relates to a kit for detection of such polymorphism.
申请公布号
WO2005014851(A2)
申请公布日期
2005.02.17
申请号
WO2004EP51711
申请日期
2004.08.04
申请人
GENE DESIGN & DEVELOPMENT S.R.L.;CIPOLLONE, FRANCESCO;MEZZETTI, ANDREA;MARTINOTTI, STEFANO