The present invention relates generally to systems and methods for improved electrochemical measurement of analytes. The preferred embodiments employ electrode systems including an analyte-measuring electrode (16a) for measuring the analyte or the product of an enzyme reaction with the analyte and an auxiliary electrode (36) configured to generate oxygen and/or reduce electrochemical interferants. Oxygen generation by the auxiliary electrode (36) advantageously improves oxygen availability to the enzyme (38) and/or counter electrode; thereby enabling the electrochemical sensors of the preferred embodiments to function even during ischemic conditions. Interferant modification by the auxiliary electrode (36) advantageously renders them substantially non-reactive at the analyte-measuring electrode, thereby reducing or eliminating inaccuracies in the analyte signal due to electrochemical interferants.
申请公布号
WO2005012873(A2)
申请公布日期
2005.02.10
申请号
WO2004US24178
申请日期
2004.07.21
申请人
DEXCOM, INC.;SIMPSON, PETER, C.;PETISCE, JAMES, R.;CARR-BRENDEL, VICTORIA;BRAUKER, JAMES, H.
发明人
SIMPSON, PETER, C.;PETISCE, JAMES, R.;CARR-BRENDEL, VICTORIA;BRAUKER, JAMES, H.