COMBINATION COMPRISING A LIPOSOME-ENCAPSULATED VINCA ALKALOID AND A TOPOISOMERASE II INHIBITOR AND THE USE THEREOF FOR TREATING NEOPLASIA

摘要

This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the co-administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, with a topoisomerase II inhibitor, e.g., etoposide or NK-611, to a mammal with a lymphoma or a sarcoma.