发明名称 |
PROCESS FOR PREPARING 6-O-MONOESTERS OF CASTANOSPERMINE |
摘要 |
The present invention relates to a process for preparing a compound of formu la (I), wherein R is C1-C10 alkyl, phenyl or substituted phenyl, comprising treating a compound of formula (II), with bis(tributyltin ) oxide in an organic solvent selected from the group consisting of o-xylene, m-xylene, p-xylene and mixed xylenes; and subsequently treating the reaction mixture with a compound of formula (III), wherein X is halogen and R is defined as above.
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申请公布号 |
CA2287316(C) |
申请公布日期 |
2005.02.08 |
申请号 |
CA19982287316 |
申请日期 |
1998.04.27 |
申请人 |
HOECHST MARION ROUSSEL, INC. |
发明人 |
LOUKS, DAVID H.;HITT, JAMES E.;GORALSKI, CHRISTIAN T.;STOLZ-DUNN, SANDRA;SCHERZER, BRIAN D.;NITZ, MARK A.;SMIT, MARK R. |
分类号 |
A61K31/437;A61P3/10;A61P31/14;A61P35/04;C07D471/04;(IPC1-7):C07D471/04 |
主分类号 |
A61K31/437 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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