发明名称 |
NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS |
摘要 |
This invention relates to nicotinamide derivatives of formula (I) and to pharmaceutical compositions containing, and the uses of such derivatives as PDE4 inhibitors wherein R7 is attached to the 3- or 4-position of the phenyl ring and is S(O)pR8, R8 is (C1-C4)alkyl optionally substituted by (C3- C6)cycloalkyl; m is 0 or 1; L is a (C3-C8)carbocyclic non-aromatic ring; and the remaining variables are as defined in the claims.
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申请公布号 |
CA2534262(A1) |
申请公布日期 |
2005.02.03 |
申请号 |
CA20042534262 |
申请日期 |
2004.07.13 |
申请人 |
PFIZER INC. |
发明人 |
BAILEY, SIMON;MIDDLETON, DONALD STUART;BARBER, CHRISTOPHER GORDON;GLOSSOP, PAUL ALAN |
分类号 |
C07D213/82;A61K31/4415;A61K31/4439;A61K31/454;A61K31/455;A61P37/00;C07D213/02;C07D401/12;C07D405/12 |
主分类号 |
C07D213/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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