| 摘要 |
<p>The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.</p> |
| 申请人 |
MERCK & CO., INC.;BURNS, DONALD, H.;CHEN, ALEX, M.;GIBSON, RAYMOND, E.;GOULET, MARK, T.;HAGMANN, WILLIAM, K.;HAMILL, TERENCE, G.;JEWELL, JAMES, P.;LIN, LINUS, S.;LIU, PING;PERESYPKIN, ANDREY, V. |
发明人 |
BURNS, DONALD, H.;CHEN, ALEX, M.;GIBSON, RAYMOND, E.;GOULET, MARK, T.;HAGMANN, WILLIAM, K.;HAMILL, TERENCE, G.;JEWELL, JAMES, P.;LIN, LINUS, S.;LIU, PING;PERESYPKIN, ANDREY, V. |
