MEASUREMENTS IN A SUBJECT USING RESONANT RAMAN SIGNALS
摘要
Methods and systems of the present invention identify the presence of and/or the concentration of a selected analyte in a subject by: (a) illuminating a selected region of the eye of a subject with an optical excitation beam, wherein the excitation beam wavelength is selected to generate a resonant Raman spectrum of the selected analyte with a signal strength that is at least 100 times greater than Raman spectrums generated by non-resonant wavelengths and/or relative to signals of normal constituents present in the selected region of the eye; (b) detecting a resonant Raman spectrum corresponding to the selected illuminated region of the eye; and (c) identifying the presence, absence and/or the concentration of the selected analyte in the subject based on said detecting step. The apparatus may also be configured to be able to obtain biometric data of the eye to identify (confirm the identity of) the subject.
申请公布号
WO2004086939(A3)
申请公布日期
2005.02.03
申请号
WO2004US08818
申请日期
2004.03.23
申请人
CHILDRENS HOSPITAL LOS ANGELES RESEARCH INSTITUTE;CALIFORNIA INSTITUTE OF TECHNOLOGY;LAMBERT, JAMES, L.;BORCHERT, MARK, S.