发明名称 THE COMBINATION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR-1 ENHANCES GROWTH
摘要 A method is disclosed for enhancing growth of a mammal by administration of a combination of effective amounts of IGF-I and GH so as to enhance the growth of the mammal over the enhancement in growth achieved using either IGF-I or GH alone in an amount equal to that used for either IGF-I or GH, respectively, in the combination. Preferably, the mammal is a child, the IGF-I is native-sequence, mature human IGF-I or human brain IGF-I , and the GH is native-sequence, mature human GH with or without a terminal methionine. In another preferred embodiment, t he mammal is a non-human animal of economic importance such as a cow or pig.
申请公布号 CA2083159(C) 申请公布日期 2005.02.01
申请号 CA19912083159 申请日期 1991.05.31
申请人 GENENTECH, INC. 发明人 CLARK, ROSS G.;CRONIN, MICHAEL J.
分类号 A61K38/27;A61K9/00;A61K31/00;A61K38/20;A61K38/30;A61K47/10;A61K47/12;A61K47/26;A61P5/00;A61P43/00;(IPC1-7):A61K38/30 主分类号 A61K38/27
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